CD39/CD73：肿瘤免疫腺苷酸通路明星靶点
产品特点
多种属：Human, Mouse, Cynomolgus, Rabbit, Canine，可全面应用于不同种属交叉实验
高纯度：SDS-PAGE验证纯度＞95%，SEC-MALS验证纯度＞90%
多样化产品选择:预偶联磁珠
高酶活：提高底物催化效率，从而有利于药物筛选
产品高生物活性经ELISA/SPR/BLI验证
高批间一致性：严格质控为高批间一致性保驾护航
产品列表
产品验证数据
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The purity of Canine CD73, His Tag (Cat. No. CD3-C52H5) is more than 90% and the molecular weight of this protein is around 115-141 kDa verified by SEC-MALS.
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Report
Immobilized Human CD39, His Tag (Cat. No. CD9-H52H4) at 1 μg/mL (100 μL/well) can bind Anti-CD39 Antibody, Human IgG1 with a linear range of 0.1-0.8 ng/mL (QC tested).
Protocol
Immobilized Monoclonal Anti-Human CD73 Antibody, Human IgG1 at 5 μg/mL (100 μL/well) can bind Biotinylated Human CD73, His,Avitag (Cat. No. CD3-H82E3) with a linear range of 0.6-5 ng/mL (QC tested).
Protocol
Loaded Anti-CD73 MAb (Human IgG1) on AHC Biosensor, can bind Human CD73, His Tag (HPLC-verified) (Cat. No. CD3-H52H7) with an affinity constant of 0.179 nM as determined in BLI assay (ForteBio Octet Red96e) (Routinely tested).
Protocol
Anti-CD73 antibody (Human IgG1) captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human CD73, His Tag (HPLC-verified) (Cat. No. CD3-H52H7) with an affinity constant of 0.164 nM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
| 测定产品 | Human CD39 / ENTPD1 Protein, His Tag | Human CD73 / NT5E Protein, His Tag (HPLC-verified) | ||
| 水解底物 | 腺苷-5 ' -三磷酸(ATP) | 腺苷-5 ' -单磷酸(AMP) | ||
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酶活 （pmol/min/μg） |
ACRO产品 （货号：CD9-H52H4） |
竞品 |
ACRO产品 （货号：CD3-H52H7） |
竞品 |
| > 6,000 | >5,000 | >100,000 | >15,000 | |
| 测定产品 | Mouse CD39 / ENTPD2 Protein, His Tag (MALS verified) | Mouse CD73 / NT5E Protein, His Tag (active enzyme) | ||
| 水解底物 | 腺苷-5 ' -三磷酸(ATP) | 腺苷-5 ' -单磷酸(AMP) | ||
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酶活 （pmol/min/μg） |
ACRO产品 （货号：CD9-M52H3） |
竞品 |
ACRO产品 （货号：CD3-M52H9） |
竞品 |
| > 25,000 | >25,000 | >20,000 | >20,000 | |
| 测定产品 | Cynomolgus CD39 / ENTPD1 Protein, His Tag (MALS verified) (active enzyme) | Cynomolgus CD73 Protein, His Tag (active enzyme) | ||
| 水解底物 | 腺苷-5 ' -三磷酸(ATP) | 腺苷-5 ' -单磷酸(AMP) | ||
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酶活 （pmol/min/μg） |
ACRO产品 （货号：CD9-C5PH3） |
竞品 |
ACRO产品 （货号：CD3-C52H9） |
竞品 |
| >15,000 | >5,000 | >50,000 | >20,000 | |
注：同一产品在相同条件下测定酶活
预偶联生物素化CD73蛋白磁珠（货号：MBS-K022）
Immobilized 62 μg CD73 protein to 1 mg Beads can bind the Anti-CD73 Antibody with an EC50 of 0.5659 μg/mL (QC tested).
Protocol
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