Human TL1A-DR3 inhibition Kit (TR-FRET)

优势与特点（FAB）

1. Cost effective - Sufficient quantity at a lower price, accounting for dilution and pipetting losses.
2. Comprehensive validation - Validated with various antibody subtypes and antibody drugs.
3. Simple and fast operation - No complicated washing steps, significantly reducing time.
4. High batch consistency - Strict control over raw materials and finished product quality, ensuring a stable supply.
5. Accurate and reliable results - High sensitivity with minimal matrix effects.
6. High throughput capability - Supports 500 tests, ideal for high-throughput screening.
7. Fast completion - Results in just 1 hour.

产品参数（Product Specifications）

产品概述（Product Overview）

The Human TL1A-DR3 inhibition Kit (TR-FRET) is based on a homogeneous (no wash) competition TR-FRET technology (Time-Resolved Fluorescence Resonance Energy Transfer) to screening for inhibitors of human TL1A binding to human DR3 within 0.5-1 hours. It can also be used as a universal detection tool to identify the ability of TL1A to bind to human DR3.

存储（Storage）

1. Unopened kit should be stored at 2℃-8℃ upon receiving.

2. Find the expiration date on the outside packaging and do not use reagents past their expiration date.

3. The opened kit should be stored per components table. The shelf life is 30 days from the date of opening.

组分（Materials Provided）

原理（Assay Principles）

This Human TL1A-DR3 inhibition kit (TR-FRET) is based on TR-FRET technology (Time-Resolved Fluorescence Resonance Energy Transfer). Use a mixture of biotinylated human TL1A and Europium-chelate labeled streptavidin as the donor and FA labeled human DR3 protein as the acceptor.

- In the absence of inhibitors for human TL1A binding to human DR3, the donor and acceptor are in close proximity due to the binding of human TL1A and FA-labeled human DR3. Upon excitation with a specific light source, the donor emits a 620 nm signal, which is absorbed by the acceptor, resulting in a 665 nm emission.

- In the presence of inhibitors that block the binding of human TL1A to human DR3, the donor-acceptor interaction is disrupted, preventing FRET from occurring.

质量管理控制体系（QMS）

1. 质量管理体系（ISO, GMP）
2. 质量优势
3. 质控流程