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JAK1

JAK1信息

英文名称:Tyrosine-protein kinase JAK1上市药物数量9
中文名称酪氨酸蛋白激酶JAK1临床药物数量41
靶点别称JAK1B，Tyrosine-protein kinase JAK1，JAK1，Janus Kinase 1，JAK1A，EC 2.7.10.2，JAK-1，JTK3，EC:2.7.10.2，EC 2.7.10最高研发阶段批准上市
英文名称:Tyrosine-protein kinase JAK1
中文名称酪氨酸蛋白激酶JAK1
靶点别称JAK1B，Tyrosine-protein kinase JAK1，JAK1，Janus Kinase 1，JAK1A，EC 2.7.10.2，JAK-1，JTK3，EC:2.7.10.2，EC 2.7.10
上市药物数量9
临床药物数量41
最高研发阶段Approved

JAK1产品列表

  • 属性

    Protein (1)

  • 产品库

    在线 (1)

  • 物种

    Human (1)

  • 标签

    His Tag (1)

  • 标记

    Unconjugated (1)

共 1 项数据
  • 1

JAK1分子背景

JAK1 is a human tyrosine kinase protein essential for signaling for certain type I and type II cytokines. It interacts with the common gamma chain (γc) of type I cytokine receptors, to elicit signals from the IL-2 receptor family (e.g. IL-2R, IL-7R, IL-9R and IL-15R), the IL-4 receptor family (e.g. IL-4R and IL-13R), the gp130 receptor family (e.g. IL-6R, IL-11R, LIF-R, OSM-R, cardiotrophin-1 receptor (CT-1R), ciliary neurotrophic factor receptor (CNTF-R), neurotrophin-1 receptor (NNT-1R) and Leptin-R). Jak1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body

JAK1分子别名

JAK1,JAK-1,JAK1A,JAK1B,Jak1
  • 分子信息
  • 产品列表