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HLA-A*02:01 & B2M & NY-ESO-1

HLA-A*02:01 & B2M & NY-ESO-1产品列表

  • 属性

    Protein (4)

  • 产品库

    在线 (4)

  • 物种

    Human (4)

  • 标签

    His Tag (2)His Tag & Avi Tag (2)

  • 标记

    Unconjugated (2)Biotin-labeled (2)

共 4 项数据
  • 1

HLA-A*02:01 & B2M & NY-ESO-1分子背景

NY-ESO-1, which is also well-known as New York esophageal squamous cell carcinoma 1, is an efficient target for cancer immunotherapy. This antigen is a member of cancer-testis antigens (CTAs) and is highly expressed in various cancers, including melanoma, ovarian, cervical cancer, etc. Adoptive T cell therapy with HLA-A2 restricted NY-ESO-1 transduced CD8+ T cells has improved the clinical response rates and overall survival of treatment-refractory melanoma patients.

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