COMP
COMP信息
| 英文名称: | Sodium channel protein type VIII alpha subunit | 上市药物数量 | 1 |
| 中文名称 | VIII型钠通道蛋白α亚基 | 临床药物数量 | 3 |
| 靶点别称 | MYOCL2，Sodium Channel， Voltage Gated， Type VIII， Alpha Subunit，Sodium Channel， Voltage Gated， Type VIII Alpha Subunit，NAV1.6 Voltage-Gated Sodium Channel，Sodium channel protein type 8 subunit alpha，Sodium channel protein type VIII subunit alpha，MED，SCN8A，Sodium Voltage-Gated Channel Alpha Subunit 8，Voltage-Gated Sodium Channel Subunit Alpha Nav1.6，Sodium Channel， Voltage Gated， Type VIII， Alpha Polypeptide，Voltage-Gated Sodium Channel Type VIII Alpha Protein，HNa6/Scn8a Voltage-Gated Sodium Channel，CERIII，EIEE13，Nav1.6，BFIS5，PN4，NaCh6，CIAT | 最高研发阶段 | 批准上市 |
| 英文名称: | Sodium channel protein type VIII alpha subunit |
| 中文名称 | VIII型钠通道蛋白α亚基 |
| 靶点别称 | MYOCL2，Sodium Channel， Voltage Gated， Type VIII， Alpha Subunit，Sodium Channel， Voltage Gated， Type VIII Alpha Subunit，NAV1.6 Voltage-Gated Sodium Channel，Sodium channel protein type 8 subunit alpha，Sodium channel protein type VIII subunit alpha，MED，SCN8A，Sodium Voltage-Gated Channel Alpha Subunit 8，Voltage-Gated Sodium Channel Subunit Alpha Nav1.6，Sodium Channel， Voltage Gated， Type VIII， Alpha Polypeptide，Voltage-Gated Sodium Channel Type VIII Alpha Protein，HNa6/Scn8a Voltage-Gated Sodium Channel，CERIII，EIEE13，Nav1.6，BFIS5，PN4，NaCh6，CIAT |
| 上市药物数量 | 1 |
| 临床药物数量 | 3 |
| 最高研发阶段 | Approved |
COMP产品列表
- 属性
Protein (1)
- 产品库
在线 (1)
- 物种
Human (1)
- 标签
His Tag (1)
- 标记
Unconjugated (1)
共 1 项数据
- 1
COMP分子背景
Cartilage oligomeric matrix protein (COMP) is also known as Thrombospondin-5 (TSP5), EDM1, EPD1, MED, PSACH, THBS5, which belongs to the thrombospondin family. COMP / TSP5 contains 4 EGF-like domains, 1 TSP C-terminal (TSPC) domain, 8 TSP type-3 repeats. Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. COMP may play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. COMP can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Thrombospondin-5 could play a role in the pathogenesis of osteoarthritis. COMP is a marker of cartilage turnover.
COMP分子别名
COMP,TSP5,EDM1,EPD1,MED,PSACH,THBS5
- 分子信息
- 产品列表