收藏产品 产品信息
分子别名（Synonym）
BXMAS1, CD307, CD307e, FCRH5, IRTA2, PRO820
表达区间及表达系统（Source）
Human FCRL5 Protein, His Tag (FC5-H52H3) is expressed from human 293 cells (HEK293). It contains AA Gln 16 - Gly 851 (Accession # Q96RD9-1).
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蛋白结构（Molecular Characterization）
This protein carries a polyhistidine tag at the C-terminus
The protein has a calculated MW of 93.3 kDa. The protein migrates as 105-125 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素（Endotoxin）
Less than 0.01 EU per μg by the LAL method.
纯度（Purity）
>90% as determined by SDS-PAGE.
>90% as determined by SEC-MALS.
制剂（Formulation）
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法（Reconstitution）
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储（Storage）
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
- -20°C to -70°C for 12 months in lyophilized state;
- -70°C for 3 months under sterile conditions after reconstitution.
产品数据图
电泳（SDS-PAGE）
Human FCRL5 Protein, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained with Coomassie Blue. The purity of the protein is greater than 90% (With Star Ribbon Pre-stained Protein Marker).
SEC-MALS
The purity of Human FCRL5 Protein, His Tag (Cat. No. FC5-H52H3) is more than 90% and the molecular weight of this protein is around 95-125 kDa verified by SEC-MALS.
Report
活性（Bioactivity）-SPR
Human FCRL5 Protein, His Tag (Cat. No. FC5-H52H3) capture on NTA-Series S sensor chip can bind Ipilimumab with an affinity constant of 28.0 μM as determined in a SPR assay (Biacore 8K) (Routinely tested).
Protocol
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背景
May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.
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