免费注册

TACI

TACI信息

英文名称:Tumor necrosis factor receptor superfamily member 13B上市药物数量0
中文名称肿瘤坏死因子受体13B基因临床药物数量1
靶点别称Transmembrane activator and CAML interactor，CD267，TACI最高研发阶段临床一期
英文名称:Tumor necrosis factor receptor superfamily member 13B
中文名称肿瘤坏死因子受体13B基因
靶点别称Transmembrane activator and CAML interactor，CD267，TACI
上市药物数量0
临床药物数量1
最高研发阶段Phase 1 Clinical

TACI产品列表

  • 属性

    Protein (3)Cell (1)

  • 产品库

    在线 (4)

  • 物种

    Human (4)

  • 标签

    Fc Tag & Avi Tag (1)Fc Tag (1)His Tag (1)

  • 标记

    Biotin-labeled (1)Unconjugated (2)

共 4 项数据
  • 1

TACI分子背景

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL.The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.

TACI分子别名

CD267,TACI,TNFRSF13B
  • 分子信息
  • 产品列表