免费注册

Prolactin R

Prolactin R信息

英文名称:Prolactin receptor上市药物数量0
中文名称催乳素受体临床药物数量1
靶点别称PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin最高研发阶段临床二期
英文名称:Prolactin receptor
中文名称催乳素受体
靶点别称PRL-R，PRLR，Prolactin Receptor，Secreted Prolactin Binding Protein，HPRL Receptor，RI-PRLR，HPRLrI，HPRL，MFAB，Receptors， Prolactin
上市药物数量0
临床药物数量1
最高研发阶段Phase 2 Clinical

Prolactin R产品列表

  • 属性

    Protein (2)

  • 产品库

    在线 (2)

  • 物种

    Human (2)

  • 标签

    Fc Tag (1)His Tag (1)

  • 标记

    Unconjugated (2)

共 2 项数据
  • 1

Prolactin R分子背景

As a transmembrane receptor, the prolactin receptor (PRL-R) interacts with prolactin. In addition, the PRL-R also binds and is activated by growth hormone (GH) and human placental lactogen (hPL). Preclinical investigations, epidemiological studies and analyses of tissue specimens from patients strongly support the contribution of prolactin receptor (PRLR) signaling to breast and prostate tumorigenesis and cancer progression. Moreover, The PRLR has been found to be essential for lobuloalveolar maturation of the mammary glands during pregnancy, as evidenced by the fact that PRLR knockout mice show severely impaired development of lobuloalveolar structures.

Prolactin R分子别名

Prolactin R,PRLR,PRL-R
  • 分子信息
  • 产品列表