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MAdCAM-1

MAdCAM-1信息

英文名称:Mucosal addressin cell adhesion molecule-1上市药物数量1
中文名称黏膜地址素细胞黏附分子-1临床药物数量2
靶点别称Mucosal addressin cell adhesion molecule 1，MADCAM1，hMAdCAM-1，Mucosal Vascular Addressin Cell Adhesion Molecule 1，MACAM1，MAdCAM-1，Mucosal Addressin Cell Adhesion Molecule-1最高研发阶段批准上市
英文名称:Mucosal addressin cell adhesion molecule-1
中文名称黏膜地址素细胞黏附分子-1
靶点别称Mucosal addressin cell adhesion molecule 1，MADCAM1，hMAdCAM-1，Mucosal Vascular Addressin Cell Adhesion Molecule 1，MACAM1，MAdCAM-1，Mucosal Addressin Cell Adhesion Molecule-1
上市药物数量1
临床药物数量2
最高研发阶段Approved

MAdCAM-1产品列表

  • 属性

    Protein (5)

  • 产品库

    在线 (5)

  • 物种

    Human (3)Cynomolgus (1)Mouse (1)

  • 标签

    Fc Tag (1)Fc Tag & Avi Tag (1)His Tag (1)His Tag & Avi Tag (2)

  • 标记

    Unconjugated (2)Biotin-labeled (3)

共 5 项数据
  • 1

MAdCAM-1分子背景

The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) takes a key role in the endothelial adhesion and migration of lymphocytes to sites of inflammation in inflammatory disease. In vitro and in vivo data indicate that blockade of the adhesion molecule mucosal address in cell adhesion molecule (MAdCAM) pathway decreases leukocyte homing to the gut by inhibiting the interaction between MAdCAM and its ligand the α4β7 integrin expressed on lymphocytes.

MAdCAM-1分子别名

MAdCAM-1,MAdCAM1,Mucosal vascular addressin cell adhesion molecule 1 transcript variant 1
  • 分子信息
  • 产品列表