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HMGB1

HMGB1信息

英文名称:High Mobility Group Protein B1上市药物数量0
中文名称高迁移率族蛋白B1临床药物数量2
靶点别称FM1 Gene Product，HMG 1 Protein，HMG-1 Protein，HMG1，Heparin-Binding Protein p30，High Mobility Group Box 1，High-Mobility Group (Nonhistone Chromosomal) Protein 1，High Mobility Group Protein B1，High Mobility Group Protein 1，HMG-1，Sulfoglucuronyl Carbohydrate Binding Protein，Amphoterin，Box Protein 1， High Mobility Group，SBP-1，High-Mobility Group Box 1，DKFZp686A04236，HMGB1最高研发阶段临床一期
英文名称:High Mobility Group Protein B1
中文名称高迁移率族蛋白B1
靶点别称FM1 Gene Product，HMG 1 Protein，HMG-1 Protein，HMG1，Heparin-Binding Protein p30，High Mobility Group Box 1，High-Mobility Group (Nonhistone Chromosomal) Protein 1，High Mobility Group Protein B1，High Mobility Group Protein 1，HMG-1，Sulfoglucuronyl Carbohydrate Binding Protein，Amphoterin，Box Protein 1， High Mobility Group，SBP-1，High-Mobility Group Box 1，DKFZp686A04236，HMGB1
上市药物数量0
临床药物数量2
最高研发阶段Phase 1 Clinical

HMGB1产品列表

  • 属性

    Protein (3)

  • 产品库

    在线 (3)

  • 物种

    Human (2)Mouse (1)

  • 标签

    His Tag (2)Mouse IgG Fc Tag (1)

  • 标记

    Unconjugated (3)

共 3 项数据
  • 1

HMGB1分子背景

High-mobility group protein B1 (HMGB1) is also known as high-mobility group protein 1 (HMG-1) and amphoterin, is a member of the HMGB family consisting of three members, HMGB1, HMGB2 and HMGB3. HMGB1 is a non-histone architectural chromosomal protein ubiquitously present in all vertebrate nuclei and binds double-stranded DNA without sequence specificity. The mechanism of inflammation and damage is binding to TLR4, which mediates HMGB1-dependent activation of macrophage cytokine release. This positions HMGB1 at the intersection of sterile and infectious inflammatory responses. HMGB1 has been studied as a DNA vaccine adjuvant and a target for cancer therapy.

HMGB1分子别名

HMGB1,HMG1,HMG3,SBP-1
  • 分子信息
  • 产品列表