ALPL
ALPL信息
| 英文名称: | Alkaline phosphatase, tissue-nonspecific isozyme | 上市药物数量 | 1 |
| 中文名称 | 非组织特异性碱性磷酸酶 | 临床药物数量 | 3 |
| 靶点别称 | Alkaline Phosphatase， Biomineralization Associated，EC:3.1.3.1，Alkaline Phosphatase Liver/Bone/Kidney Isozyme，Liver/Bone/Kidney-Type Alkaline Phosphatase，ALPL，AP-TNAP，Alkaline Phosphatase， Liver/Bone/Kidney，Tissue Non-Specific Alkaline Phosphatase，TNSALP，Alkaline Phosphatase， Tissue-Nonspecific Isozyme，Tissue-Nonspecific ALP，EC 3.1.3.1，APTNAP，TNALP，TNAP，HOPS | 最高研发阶段 | 批准上市 |
| 英文名称: | Alkaline phosphatase, tissue-nonspecific isozyme |
| 中文名称 | 非组织特异性碱性磷酸酶 |
| 靶点别称 | Alkaline Phosphatase， Biomineralization Associated，EC:3.1.3.1，Alkaline Phosphatase Liver/Bone/Kidney Isozyme，Liver/Bone/Kidney-Type Alkaline Phosphatase，ALPL，AP-TNAP，Alkaline Phosphatase， Liver/Bone/Kidney，Tissue Non-Specific Alkaline Phosphatase，TNSALP，Alkaline Phosphatase， Tissue-Nonspecific Isozyme，Tissue-Nonspecific ALP，EC 3.1.3.1，APTNAP，TNALP，TNAP，HOPS |
| 上市药物数量 | 1 |
| 临床药物数量 | 3 |
| 最高研发阶段 | Approved |
ALPL产品列表
- 属性
Protein (2)
- 产品库
在线 (2)
- 物种
Human (2)
- 标签
His Tag (2)
- 标记
Unconjugated (1)HRP Labeled (1)
共 2 项数据
- 1
ALPL分子背景
This gene encodes a member of the alkaline phosphatase family of proteins. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature enzyme. This enzyme may play a role in bone mineralization. Mutations in this gene have been linked to hypophosphatasia, a disorder that is characterized by hypercalcemia and skeletal defects.
ALPL分子别名
AP-TNAP, APTNAP, HOPS, HPPA, HPPC, HPPI, HPPO, TNALP, TNAP, TNS-ALP, TNSALP
- 分子信息
- 产品列表