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LILRB2

LILRB2信息

英文名称:Leukocyte immunoglobulin-like receptor subfamily B member 2上市药物数量0
中文名称白细胞免疫球蛋白样受体亚家族B成员2临床药物数量9
靶点别称Leukocyte immunoglobulin-like receptor 2,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,ILT-4,Monocyte/macrophage immunoglobulin-like receptor 10,MIR-10,CD_antigen: CD85d,LILRB2,Leukocyte Immunoglobulin Like Receptor B2,Leucocyte Ig-Like Receptor B2,MIR10,Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM And ITIM Domains), Member 2,Ig-Like Transcript 4,Myeloid Inhibitory Receptor 10,CD85d Antigen,ILT4,LIR2,CD85d,LIR-2,LIRB2最高研发阶段Phase 2 Clinical
英文名称:Leukocyte immunoglobulin-like receptor subfamily B member 2
中文名称白细胞免疫球蛋白样受体亚家族B成员2
靶点别称Leukocyte immunoglobulin-like receptor 2,CD85 antigen-like family member D,Immunoglobulin-like transcript 4,ILT-4,Monocyte/macrophage immunoglobulin-like receptor 10,MIR-10,CD_antigen: CD85d,LILRB2,Leukocyte Immunoglobulin Like Receptor B2,Leucocyte Ig-Like Receptor B2,MIR10,Leukocyte Immunoglobulin-Like Receptor, Subfamily B (With TM And ITIM Domains), Member 2,Ig-Like Transcript 4,Myeloid Inhibitory Receptor 10,CD85d Antigen,ILT4,LIR2,CD85d,LIR-2,LIRB2
上市药物数量0
临床药物数量9
最高研发阶段Phase 2 Clinical

LILRB2产品列表

  • 属性

    Protein (6)

  • 产品库

    在线 (7)

  • 物种

    Human (4)Cynomolgus (2)

  • 标签

    His Tag (2)Fc Tag & Avi Tag (1)His Tag & Avi Tag (2)Fc Tag (1)

  • 标记

    Unconjugated (3)Biotin-labeled (3)

共 6 项数据
  • 1

LILRB2分子背景

Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

LILRB2分子别名

LILRB2,ILT4,LIR2,MIR10,CD85d

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