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Fc gamma RI / CD64

Fc gamma RI / CD64信息

英文名称:High affinity immunoglobulin gamma Fc receptor I上市药物数量0
中文名称高亲和力免疫球蛋白γFc受体I临床药物数量0
靶点别称IgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)最高研发阶段Discontinued
英文名称:High affinity immunoglobulin gamma Fc receptor I
中文名称高亲和力免疫球蛋白γFc受体I
靶点别称IgG Fc Receptor I,FcgammaRIa,High Affinity Immunoglobulin Gamma Fc Receptor I,Fc-Gamma Receptor I A1,CD64 Antigen,CD64A,CD64,FCG1,FCGR1,IGFR1,FcRI,Fc-gamma RIA,Fc-gamma RI,Fc Fragment Of IgG Receptor Ia,Fc Fragment Of IgG, High Affinity Ia, Receptor (CD64),Fc Gamma Receptor Ia,FCGR1A,Fc Fragment Of IgG, High Affinity Ia, Receptor For (CD64)
上市药物数量0
临床药物数量0
最高研发阶段Discontinued

Fc gamma RI / CD64产品列表

  • 属性

    Protein (8)Cell (4)Kits (1)

  • 产品库

    在线 (13)

  • 物种

    Mouse (2)Human (7)Cynomolgus (2)Canine (1)Rat (1)

  • 标签

    His Tag (5)His Tag & Avi Tag (3)

  • 标记

    Unconjugated (5)Biotin-labeled (3)

共 13 项数据
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Fc gamma RI / CD64分子背景

Receptors that recognize the Fc portion of IgG are divided into three groups designated Fc gamma RI, RII, and RIII, also known respectively as CD64, CD32, and CD16. Fc gamma RI binds IgG with high affinity and functions during early immune responses. Fc gamma RII and RIII are low affinity receptors that recognize IgG as aggregates surrounding multivalent antigens during late immune responses.High affinity immunoglobulin gamma Fc receptor I is also known as FCGR1A, FCG1, FCGR1, CD64 and IGFR1, is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity, which belongs to the immunoglobulin superfamily or FCGR1 family. FCGR1A / CD64 contains 3 Ig-like C2-type (immunoglobulin-like) domains. CD64 is constitutively found on only macrophages and monocytes, but treatment of polymorphonuclear leukocytes with cytokines like IFNγ and G-CSF can induce CD64 expression on these cells.

Fc gamma RI / CD64分子别名

FCGR1A,FCG1,FCGR1,IGFR1,CD64,CD64A,FCRI

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